CNG Channel beta 1/truncated GARP (AA 851-950) anticorps

N° du produit ABIN1386515

L’anticorps Lapin Polyclonal anti- a été validé pour IF (cc), IF (p), ELISA, IHC (fro), IHC (p) et ICC. Il convient pour détecter dans des échantillons de Humain.

Aperçu rapide pour CNG Channel beta 1/truncated GARP (AA 851-950) anticorps (ABIN1386515)

Antigène: CNG Channel beta 1/truncated GARP

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit

Épitope: AA 851-950

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human truncated GARP

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CNG Channel beta 1/truncated GARP

Sujet:

Synonyms: CNG4, GAR1, GARP, RP45, CNCG2, CNCG4, GARP2, RCNC2, RCNCb, CNCG3L, CNGB1B, RCNCbeta, Cyclic nucleotide-gated cation channel beta-1, Cyclic nucleotide-gated cation channel 4, CNG channel 4, CNG-4, Cyclic nucleotide-gated cation channel gamma, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-1, CNG channel beta-1, Glutamic acid-rich protein, CNGB1

Background: Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties: it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit.

ID gène: 1258

UniProt: Q14028